Pay as little as $28 per month*
Naprelan® is indicated to treat mild to moderate pain. It can begin to work within 30 minutes and is formulated to last for 24 hours, so you only have to take it once a day. It is available in 375 mg, 500 mg and 750 mg tablets.
*Terms and Conditions apply.
Download Full Prescribing Information including Boxed WARNING and Medication Guide


NAPRELAN® may be used to treat rheumatoid arthritis, osteoarthritis, ankylosing spondylitis, tendinitis, bursitis, and acute gout. It may also be used to relieve mild to moderate pain and the treatment of primary dysmenorrhea (menstrual cramps).


NAPRELAN ® is a non-steroidal anti-inflammatory drug (NSAID). Like all NSAIDS, it can cause an increased risk of a heart attack or stroke that can lead to death. This risk may occur early in treatment and may increase by taking higher doses or with longer use.

NAPRELAN ® should not be taken right before or after a heart surgery called a coronary artery bypass graft (CABG), or after a recent heart attack.

Bleeding, ulcers, and tears of the esophagus, stomach and intestines may occur without warning anytime during use and may cause death. These risks increase in patients taking certain medications, those who smoke or drink alcohol, and the elderly.

You should not take NAPRELAN ® if you have had an asthma attack, hives or other allergic reaction with aspirin or any other NSAIDs.

Tell your doctor if you have liver or kidney problems, high blood pressure, asthma, pregnant or plan to become pregnant or breastfeeding.

Taking NSAIDs at about 20 weeks of pregnancy or later may harm your unborn baby. If you need to take NSAIDs for more than 2 days when you are between 20 and 30 weeks of pregnancy, your healthcare provider may need to monitor the amount of fluid in your womb around your baby. You should not take NSAIDs after about 30 weeks of pregnancy.

NAPRELAN ® can cause new or worse high blood pressure, heart failure, liver problems including liver failure, kidney problems including kidney failure, and low red blood cells (anemia).

Life threatening allergic reactions, including serious skin reactions can occur with NAPRELAN ® .

Get emergency help right away if you have shortness of breath or trouble breathing, chest pain, weakness in one part or side of your body, slurred speech, swelling of the face or throat.

NAPRELAN ® should be used exactly as prescribed at the lowest dose possible and for the shortest time needed.

These are not all of the side effects associated with NAPRELAN®. Please see full prescribing information for additional safety information on .

You are encouraged to report negative side effects of prescription drugs to Almatica at 1-877-447-7979 or the FDA at or call 1-800-FDA-1088 .