NAPRELAN® Naproxen Sodium

Patients

IMPORTANT SAFETY INFORMATION
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All NSAIDs, including NAPRELAN^®, have the same cardiovascular warning: They may increase the chance of heart attack or stroke that can lead to death. This chance increases with longer use of NSAID medicines and in people who have heart disease.

The NAPRELAN^® Co-Pay Card helps you save!


	Click here for Important Eligibility Information

With the NAPRELAN^® Co-Pay Card, eligible patients pay only $15 for new prescriptions and $7.50 for refills on co-pays up to $100.*
Click here to learn if you are eligible.

Here's how to take advantage of this offer:

Download the NAPRELAN^® Co-Pay Card (click here) and print it out. Be sure to print all pages.

Bring the card and your NAPRELAN^® prescription to your pharmacy.

It's that simple!

Attention: Patients are responsible for at least the initial $15.00 for the first prescription, and at least the initial $7.50 for refill prescriptions. This offering is valid for both cash paying and insured patients. This certificate provides a maximum benefit of up to $85.00 for the first prescription, and up to $92.50 for refill prescriptions for both cash paying and eligible insured patients. The amount collected is determined by the patient co-pay, if applicable. For insured patients, if the total out of pocket pharmacy bill exceeds $100.00 the patient will be responsible for the additional balance. The pharmacist will determine the total out of pocket payment for the patient. Cash paying customers will receive up to $85.00 off their pharmacy cash price on the first prescription and up to $92.50 off of each refill up to 11 refills. This certificate will cover the initial prescription plus up to 11 refills.

	Important Eligibility Rules
	This coupon is not valid for prescriptions reimbursed under Medicare, Medicaid, Tricare or any other federal or state program, or where prohibited by law. Where third party reimbursement covers a portion of your prescription, this coupon is valid only for the amount of your actual out-of-pocket expenses up to a maximum of $85.00 for first fills and up to a maximum of $92.50 for refills. Offer valid only for prescriptions filled in the United States. Shionogi Inc. reserves the right to discontinue this offer at any time. It is a violation of federal law to buy, sell, or counterfeit this certificate.

	Offer void in Massachusetts except for patients with no prescription drug insurance coverage.

	Offer expires: December 31, 2012

Indications

NAPRELAN^® Tablets are indicated for the treatment of rheumatoid arthritis, osteoarthritis, ankylosing spondylitis, tendinitis, bursitis, and acute gout. It is also indicated in the relief of mild to moderate pain and the treatment of primary dysmenorrhea.

Important Safety Information

NAPRELAN^® belongs to a class of medicines called nonsteroidal anti-inflammatory drugs (NSAIDs). NSAID medicines are used to treat pain and redness, swelling, and heat (inflammation) from medical conditions such as:
• different types of arthritis
• menstrual cramps and other types of short-term pain

All NSAIDs, including NAPRELAN^®, have the same cardiovascular warning: They may increase the chance of heart attack or stroke that can lead to death. This chance increases with longer use of NSAID medicines and in people who have heart disease.

NAPRELAN^® should never be used right before or after a heart surgery called a coronary artery bypass graft (CABG).

NAPRELAN^® can cause ulcers and bleeding in the stomach and intestines at any time during treatment. This can happen without warning symptoms and may cause death. Patients taking aspirin and the elderly are at an increased risk.

Serious skin reactions, or allergic reactions, sometimes fatal, can occur without warning and have been reported with NAPRELAN^® use. Do not take NAPRELAN^® if you are allergic to naproxen, or have had an asthma attack, hives, or other allergic reactions when taking aspirin or another NSAID medicine.

Get emergency help right away if you have shortness of breath or trouble breathing, chest pain, weakness in one part or side of your body, slurred speech, swelling of the face or throat.

Before using NAPRELAN^®, talk to your health care professional about all of your medical conditions and the medications you take, and if you are pregnant, planning to become pregnant, or breast-feeding. NAPRELAN^® should not be taken in late pregnancy.

NAPRELAN^® should be used exactly as prescribed at the lowest dose possible and for the shortest time needed.

The most frequent side effects that have been reported with NAPRELAN^® are headache, heartburn, and flu syndrome. Other side effects that may occur include back pain, other types of pain, infection, nausea, diarrhea, constipation, abdominal pain, sore throat, runny nose, sinusitis, urinary tract infection, skin rash, skin eruptions, black and blue marks, drowsiness, excess fluid in the tissues, trouble breathing, and ringing in the ears.

For more information about NAPRELAN^® and other NSAIDs, please see the Medication Guide.

These are not all the side effects with NSAID medicines, including NAPRELAN^®. Talk to your healthcare provider or pharmacist for more information about NSAID medicines, including NAPRELAN^®.

You are encouraged to report negative side effects of prescription drugs to the FDA. Visit www.fda.gov/medwatch, or call 1-800-FDA-1088.

Click here for full Prescribing Information

NAPRELAN is a registered trademark of Alkermes Pharma Ireland Limited. (APIL).
IPDAS is a registered trademark of Alkermes Pharma Ireland Limited. (APIL). US Patent No.: US 5637320

Shionogi Inc.